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Location/Division: United Kingdom

What will you do?

• Work independently to advance our preclinical drug discovery cascades and diagnostic assays for patient stratification
• Develop and implement quantitative plate-based assays to characterize small molecule ligands and drive medicinal chemistry campaigns
• Conduct mechanism of action studies to elucidate the modes of ligand interaction and/or mechanisms of action in cell lines
• Design and execute target engagement studies
• Author and approve technical documents and carefully document lab reports
• Work collaboratively with partners to ensure the success of projects.
• Be part of building the Tessellate way of working as part of a small and growing team.

Your ideal skills and experience

• PhD in Biological Sciences
• Proven ability to independently design, develop and implement biochemical/cellular assays using technologies including but not limited to FRET, HiBIT, CETSA, high content imaging
• Hands on experience with automated liquid handling instrumentation and knowledge of high throughput data analysis workflows is highly desirable
• Understanding of biomarker identification strategies would be advantageous
• Excellent communication skills with ability to present data and goals clearly and accurately
• Strong organisation, planning and problem-solving skills
• Good relationship building